SERVICES

 

COMPOUND LIBRARY

The compound collection of 50 000 small molecules gives users access to a library consisting of compounds with high chemical diversity and lead-like physical-chemical properties. The collection which will be delivered in assay-ready plates can be used for screening at the users’ own facilities or alternatively, screening can be performed at one of the DK-OPENSCREEN screening nodes. DK-OPENSCREEN also offer ~2000 academic compounds and ~700 fluorinated fragments. For more details please contact us at info@dk-openscreen.dk


HIGH-THROUGHPUT SCREENING

The fully automated DTU Screening Core platform is design to perform biochemical and cell-based assays in 96-, 384- and 1536-well plate format, with great flexibility in terms of possible read-outs, thanks to the Tecan Spark Cyto 600 multimode microplate reader with cell-imaging function. 

We offer:

  • Assay development
  • Assay adaptation and miniaturization in HTS format
  • Pilot screening
  • Full library screening
  • Focused subset library screening
  • Hit confirmation
  • Potency determination
  • Data analysis
  • Compound toxicity in Cell viability assays

 

https://www.dk-openscreen.dk/services
23 APRIL 2024